The Effects of the Acidic Metabolites from the Ethanol Root Extracts Lonchocarpus Cyanecsens, Curciligo Pilosa, Securidaca Longipendiculata, Theobroma Cacao on Pseudomonas Aeruginosa

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Year:
2015
Type of Publication:
Article
Keywords:
Acidic, Antibacterial, Extract, Metabolites, Roots
Authors:
D.C Nwokonkwo; I. Ikelle Ikelle
Journal:
IJISM
Volume:
3
Number:
2
Pages:
67-69
Month:
March
ISSN:
2347-9051
Abstract:
The effects of the acidic metabolites of the ethanol extracts of the roots of lonchocarpus cyanescens, curciligo pilosa, securidaca longipendunculata and Theobroma cacao on Pseudomonas aeruginosa was the focus of this investigation. The acidic metabolites obtained by partitioning the crude samples of the root extracts showed that the root of lonchocarpus cyanescens contained flavonoids, alkaloids, tannins, saponins, glycosides and phenols. The root of curciligo pilosa had saponins, flavonoids, alkaloids, glycosides and phenols. The acidic root extract of securidaca longipendunculata indicated the presence of tannins, flavonoids, glycosides and alkaloids. While tannins, saponins, flavonoids, alkaloids, glycosides and phenols were found in Theobroma cacao. The antibacterial screening of the extracts showed minimum inhibitory concentration (MIC) at a concentration of 100mg/mL with inhibition zone diameter (IZD) of 36 millimeter (mm) for lonchocarpus cyanescens, 00 mm for curciligo pilosa, 20 mm for securidaca longipendunculata and 30mm for Theobroma cacao. The IZD of the reference drug ampiclox at the same concentration of 100mg/mL was 25mm for lonchocarpus cyanescens 26mm for curciligo pilosa, 20mm for securidaca longipendunculata and 28mm for Theobroma cacao. Lonchocarpus cyanescens gave the highest activity at IZD of 36 mm while Curculigo pilosa gave no inhibitory activity
Full text: IJISM-346_Final.pdf

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